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Age-related changes in the gonadal environment: impact on fertility of quail oocytes.
The aim of this study was to determine the impact of aging on the in vitro maturation and fertilization of quail (Coturnix coturnix japonica) oocytes and subsequent ability of oocytes to produce offspring. Our results showed that the age-related decrease in the percentage of oocytes that matured in vitro was only partially compensated by an increase in the number of fertilized oocytes. The rate of blastulation was lower and the hatching rate was lower. The number of offspring was significantly lower. These findings emphasize the need for very specific culture conditions and for the maintenance of optimal physiological levels of hormones in the gonadal environment of growing female quails.Colonic diverticulosis and risk of cardiovascular disease.
The association between diverticulosis and cardiovascular disease (CVD) remains unclear. We sought to investigate the association between diverticulosis and CVD in a large, single-center cohort. Colonoscopy was performed in 1169 asymptomatic individuals. CVD and its risk factors ac619d1d87
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